Injectables have become increasingly popular for addressing early signs of ageing, but not all treatments work the same way. If you’ve been researching aesthetic options, you’ve likely come across both Profhilo and dermal fillers. While they may appear similar at first glance, they serve very different purposes.
If you’re trying to decide which injectable suits your goals, it’s important to understand how each works. This article compares Profhilo vs fillers, from formulation and function to outcomes and ideal candidates, so you can make a more informed decision about your next profhilo treatment.
What Are Dermal Fillers?
Dermal fillers are injectable substances, most often made of cross-linked hyaluronic acid, designed to add volume to targeted areas. They can:
- Fill deep wrinkles or folds
- Enhance lips and cheeks
- Restore lost facial volume due to ageing
Because they hold their shape, fillers are ideal for lifting, contouring, and reshaping the face.
What Is Profhilo?
Profhilo is also made of hyaluronic acid, but it’s a stabilised, non-cross-linked form. Instead of staying in one spot, it spreads beneath the skin to hydrate and stimulate the production of collagen and elastin. It improves overall skin tone, elasticity, and texture without adding volume.
Think of Profhilo as a skin bio-remodelling treatment rather than a contouring filler.
Key Differences at a Glance
| Feature | Profhilo | Dermal Fillers |
| Purpose | Skin hydration and collagen stimulation | Volume restoration and facial contouring |
| Formula | Non-cross-linked hyaluronic acid | Cross-linked hyaluronic acid |
| Consistency | Flows and spreads under the skin | Stays in place to hold shape |
| Treatment Areas | Cheeks, lower face, neck, décolletage | Cheeks, lips, jawline, nasolabial folds |
| Effect on Appearance | Improves skin quality and texture | Lifts, fills, and defines facial features |
| Longevity | 6–9 months | 9–18 months (varies by product/area) |
Which One Should You Choose?
Choose Profhilo If You:
- Want better skin hydration and glow
- Have dull, crepey, or sagging skin
- Prefer a natural-looking, subtle result
- Are looking to improve skin elasticity without altering facial shape
- Have early signs of skin ageing but don’t yet need volume restoration
Choose Fillers If You:
- Want to restore lost volume in cheeks or temples
- Wish to define or sculpt facial features like the jawline or chin
- Have deeper lines or folds needing structure
- Are looking for more immediate and dramatic enhancement
Can You Combine Profhilo and Fillers?
Yes. Many clinics recommend a combined approach when appropriate. For example, Profhilo can improve overall skin quality while fillers restore shape. The two work synergistically; one treats the skin, the other treats the structure beneath it.
However, they’re usually not done on the same day. Your provider will assess your skin goals and sequence treatments accordingly.
What to Expect from Each Treatment
| Aspect | Profhilo | Fillers |
| No. of Sessions | Usually 2 sessions, 4 weeks apart | Varies (1 session often sufficient) |
| Injection Points | 5 points per side of the face | Customised based on treatment goals |
| Downtime | Minimal (mild swelling, no bruising) | Mild swelling, possible bruising |
| Result Timeline | Gradual over 4–6 weeks | Immediate |
| Maintenance | Every 6–9 months | Every 9–18 months |
Final Thoughts
Choosing between Profhilo and fillers depends on your individual skin needs and aesthetic goals. If you’re looking to boost hydration, elasticity, and overall skin quality, Profhilo may be a better option. If your goal is facial volume and contouring, then fillers are likely more suitable.
There’s no one-size-fits-all answer. The best results often come from a personalised plan created with a qualified provider who understands how to balance skin health with structural support.